益骨口服液能夠顯著提高實(shí)驗(yàn)性骨質(zhì)疏松模型大鼠的載荷,提示益骨口服液在有效抑制模型鼠股骨干材料和結(jié)構(gòu)的變化方面有確切的作用,F(xiàn)代醫(yī)學(xué)認(rèn)為,骨質(zhì)疏松癥是由于骨代謝失調(diào),骨的丟失大于骨的重建,結(jié)果導(dǎo)致骨量丟失,骨小梁結(jié)構(gòu)破壞,骨強(qiáng)度下降,而導(dǎo)致骨折風(fēng)險(xiǎn)升高的一種全身性代謝障礙的退行性骨骼疾病[48]。臨床表現(xiàn)為腰背肢體疼痛、畸形、骨折等。中醫(yī)認(rèn)為“腎虧脾虛”是“骨枯”、“骨痿”的基本病因。骨質(zhì)疏松癥的主要癥狀是疼痛,“瘀則必痛”,“久病必瘀”是骨質(zhì)疏松癥的基本病理變化。對(duì)骨質(zhì)疏松癥的辨證論治強(qiáng)調(diào)從脾腎入手,以補(bǔ)腎益脾化瘀為治療大法。本實(shí)驗(yàn)所采用益骨口服液(主要成分:山藥、枸杞、丹參、骨碎補(bǔ)、補(bǔ)骨脂等)。以骨碎補(bǔ)、補(bǔ)骨脂補(bǔ)腎壯骨,山藥、枸杞健脾養(yǎng)肝,丹參活血化瘀,有機(jī)配伍,相得益彰醫(yī).學(xué)全.在.線m.f1411.cn。
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